National Center for Construction Safety and Health Research and Translation (U54)

3 weeks 3 days ago
Funding Opportunity RFA-OH-24-001 from the NIH Guide for Grants and Contracts. The purpose of this announcement is to seek applications from qualified organizations for a National Center for Construction Safety and Health Research and Translation (also known as the NIOSH National Construction Center). Applicants are expected to propose multi-disciplinary approaches for impactful applied and intervention research and hazard identification and controls, to develop partnerships for implementing prevention and intervention activities, and to serve as leaders in research translation and research-to-practice for the protection of construction workers in the United States.

Improving Choice, Use, and Equitable Implementation of Biomedical HIV Prevention for Women (R34 Clinical Trial Optional)

3 weeks 5 days ago
Funding Opportunity RFA-MH-24-162 from the NIH Guide for Grants and Contracts. This initiative will solicit research to target gaps in knowledge about barriers and facilitators to ring use, interventions to improve uptake, adherence, and persistence on the vaginal ring, and implementation science studies to improve access to and distribution of the ring. Research topics may include, but are not limited to: studies of individual, interpersonal, and structural factors that are barriers and facilitators to uptake of, adherence to, and persistence on the vaginal ring when the ring is delivered in real world settings (i.e., outside of clinical or open label extension trials); development and testing of behavioral interventions to encourage uptake, consistent use of, and persistence on the vaginal ring; and implementation science studies to understand implementation barriers and facilitators to delivery of the vaginal ring, and to optimize delivery of the ring.

Improving Choice, Use, and Equitable Implementation of Biomedical HIV Prevention for Women (R21 Clinical Trial Optional)

3 weeks 5 days ago
Funding Opportunity RFA-MH-24-161 from the NIH Guide for Grants and Contracts. This initiative will solicit research to target gaps in knowledge about barriers and facilitators to ring use, interventions to improve uptake, adherence, and persistence on the vaginal ring, and implementation science studies to improve access to and distribution of the ring. Research topics may include, but are not limited to: studies of individual, interpersonal, and structural factors that are barriers and facilitators to uptake of, adherence to, and persistence on the vaginal ring when the ring is delivered in real world settings (i.e., outside of clinical or open label extension trials); development and testing of behavioral interventions to encourage uptake, consistent use of, and persistence on the vaginal ring; and implementation science studies to understand implementation barriers and facilitators to delivery of the vaginal ring, and to optimize delivery of the ring.

Improving Choice, Use, and Equitable Implementation of Biomedical HIV Prevention for Women (R01 Clinical Trial Optional)

3 weeks 5 days ago
Funding Opportunity RFA-MH-24-160 from the NIH Guide for Grants and Contracts. This initiative will solicit research to target gaps in knowledge about barriers and facilitators to ring use, interventions to improve uptake, adherence, and persistence on the vaginal ring, and implementation science studies to improve access to and distribution of the ring. Research topics may include, but are not limited to: studies of individual, interpersonal, and structural factors that are barriers and facilitators to uptake of, adherence to, and persistence on the vaginal ring when the ring is delivered in real world settings (i.e., outside of clinical or open label extension trials); development and testing of behavioral interventions to encourage uptake, consistent use of, and persistence on the vaginal ring; and implementation science studies to understand implementation barriers and facilitators to delivery of the vaginal ring, and to optimize delivery of the ring.

Single Source: Pediatric Early Phase Clinical Trials Network (PEP-CTN; UM1 Clinical Trial Required)

3 weeks 6 days ago
Funding Opportunity RFA-CA-24-007 from the NIH Guide for Grants and Contracts. Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to enhance NCIs program for conducting early phase clinical trials in children with cancer, thereby facilitating the introduction of high priority novel agents into the pediatric oncology setting in a timely manner. This ability to quickly conduct first in children studies is critical to NCIs overall clinical research program for children with cancer. The primary scope of the Pediatric Early Phase Clinical Trials Network (PEP-CTN) is to design and conduct pediatric phase 1 trials that will often include phase 2 expansion cohorts. Conduct of the phase 2 study components within the PEP-CTN is efficient and allows intensive study monitoring for toxicity for these agents undergoing their initial evaluation in children. When phase 1 testing results for an agent are available, phase 2 studies will also be within the remit of the PEP-CTN. As well, the PEP-CTN will conduct pilot studies of novel regimens to determine their tolerability so that they can proceed to definitive testing in phase 3 clinical trials.

Building Neuroscience Research Infrastructure for Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) in Africa (UG3/UH3 Clinical Trial Not Allowed)

3 weeks 6 days ago
Funding Opportunity RFA-AG-24-027 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) promotes collaborative research programs to support the development/enhancement of infrastructure (e.g., tools, surveys, biospecimens, data) for Alzheimer's disease (AD) and AD-related dementias (AD/ADRD) neuroscience research in low- and middle-income countries (LMICs) in Africa. Specifically, the National Institute on Aging (NIA) seeks to support Phase Innovation Awards Cooperative Agreement (UG3/UH3) projects to enable: (1) the formation of transformative collaborations between institutions/scientists in the US and LMICs in Africa; (2) the development, or enhancement of research infrastructure and resources for studies of AD/ADRD neuroscience relevant to Africaas well as to examine how social or behavioral factors influence AD/ADRD in Africa; (3) the initiation of pilot or exploratory studies that will inform future research for AD/ADRD neuroscience in Africa. These research infrastructure programs are expected to contribute to the long-term goals of building sustainable AD/ADRD neuroscience research capacity and research,ultimately leading to prevention and mitigation strategies for AD/ADRD in Africa. Income categories for LMICs in Africa are defined by the World Bank at http://data.worldbank.org/about/country-classifications/country-and-lending-groups.

Community Partnerships to Advance Science for Society (ComPASS): Health Equity Research Hubs (UC2 Clinical Trial Optional)

4 weeks ago
Funding Opportunity RFA-RM-23-012 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications from eligible organizations that can serve as Health Equity Research Hubs (Hubs) for awarded community-led health equity structural intervention (CHESI) projects within the Community Partnerships to Advance Science for Society (ComPASS) Program. The Hubs will serve as a centralized research resource, providing tailored scientific, technical, and collaborative support for sustainable community engagement, research capacity building, and training to assigned CHESI projects that address SDOH and structural factors to improve health outcomes. The Hubs are one of three complementary initiatives under the ComPASS Program, which also include the CHESI projects and the ComPASS Coordination Center.

Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access (X01)

4 weeks ago
Funding Opportunity PAR-24-027 from the NIH Guide for Grants and Contracts. The Population Assessment of Tobacco and Health (PATH) Study provides the scientific community with biospecimens (urine, plasma, serum, and genomic DNA) and related research data on behaviors, attitudes, biomarkers and health outcomes associated with tobacco use in the U.S. This opportunity allows investigators to apply for access to the biospecimens from the PATH Study. Information about the PATH Study and this resource may be found on the PATH Study series page (https://doi.org/10.3886/Series606) at the University of Michigans National Addiction and HIV Data Archive Program (NAHDAP) website, part of the Inter-University Consortium for Political and Social Researchs (ICPSR) website.

Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)

4 weeks ago
Funding Opportunity PAR-23-280 from the NIH Guide for Grants and Contracts. The goal of the proposed funding announcement is twofold, to promote preclinical and patient based studies examining the mechanism(s) through which incretin mimetics (including agonists or antagonists of GLP-1, GIP-1, or dual GLP-1/GIP-1 agents) impact cancer risk, and to draw talented scientists who understand the dynamic changes caused by these agents to investigate the mechanisms of how these agents influence cancer risk rather than shorter term outcomes such as weight loss and diabetes. The data thus far suggests that these agents may increase the risk of some, while decreasing the risk of other obesity related cancers.
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16 hours 50 minutes ago
Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
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