Funding Opportunity RFA-AI-25-035 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to support basic research to understand the fundamental mechanisms underlying human-to-human transmission of seasonal influenza virus. The NOFO will establish an Influenza Transmission Research Consortium comprised of a network of individual Influenza Transmission Research Centers. Centers should propose collaborative, multidisciplinary teams that will investigate the dynamics and drivers of influenza transmission and develop novel resources to further the field of respiratory virus transmission.

Funding Opportunity RFA-AG-26-011 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites R25 applications to support the development and implementation of summer research education programs for high school students, undergraduates, or science teachers from all backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences. It is essential to expand and broaden the skilled Alzheimer's Disease (AD) and Alzheimers Disease Related Dementias (ADRD) research workforce and provide exposure to AD/ADRD research to individuals early in their careers. The proposed research education programs will support intensive summer research experiences in the AD/ADRD field with the goal of exposing participants to AD/ADRD research and encourage further study or participation in biomedical and behavioral research. This NOFO does not allow participants to lead an independent clinical trial, but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.

Funding Opportunity RFA-AG-26-010 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity Announcement (NOFO) invites R25 applications to support the development and implementation of research education programs for recent baccalaureates from all backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences. It is essential to expand and broaden the skilled Alzheimers Disease (AD) and Alzheimers Disease and Related Dementias (ADRD) research workforce and provide exposure to AD/ADRD research to individuals early in their careers. The proposed research education programs will support intensive research experiences in the AD/ADRD field with the goal of preparing recent baccalaureates to transition into strong, research-focused advanced degree programs or competitive private sector research careers in AD-related disciplines.

Funding Opportunity RFA-AT-25-004 from the NIH Guide for Grants and Contracts. The purpose of this NOFO is to establish the NIH Blueprint for Neuroscience Research Coordination Center for Interoception Research (BPCCIR). Interoception, for the purpose of this NOFO, encompasses the processes by which an organism or a person senses, interprets, integrates, and regulates signals that represent the internal states. The goals of the NBCCIR are to: 1) promote a multidisciplinary approach for interoception research, and 2) bridge the gap between brain and body studies through a cooperative agreement funding mechanism, U24. This NOFO aims to foster interactions within the broad community of interoception researchers, rather than focusing on disease-specific subdisciplines. Specifically, the NOFO will support efforts to: 1) establish and maintain a multidisciplinary team of interoception researchers to oversee and guide NBCCIR activities; 2) create and support digital communication platforms to facilitate networking, collaborations, and information dissemination; 3) plan, organize, and host at least one scientific meeting per year that will include NIH-funded interoception researchers, trainees, and other stakeholders; 4) identify challenges and future technological and scientific opportunities for the field of interoception and develop common terminology, data standards, and common data elements; and 5) generate metrics of success and plans to ensure the sustainability of the interoception research community.

Notice NOT-AI-25-041 from the NIH Guide for Grants and Contracts

Notice NOT-CA-25-118 from the NIH Guide for Grants and Contracts

Notice NOT-OD-25-147 from the NIH Guide for Grants and Contracts

Notice NOT-OD-25-141 from the NIH Guide for Grants and Contracts

Notice NOT-OD-25-145 from the NIH Guide for Grants and Contracts

Notice NOT-OD-25-146 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-HL-26-012 from the NIH Guide for Grants and Contracts. The overall goal of the Stimulating Access to Research in Residency (StARR) program is to provide resident clinicians in training with in-depth research experiences early in their careers, in order to recruit, retain and accelerate independence of a pool of clinician-investigators with both clinical and research experience necessary to perform basic, clinical and/or translational research.

Funding Opportunity RFA-AI-25-022 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to solicit research applications focused on preclinical development of lead candidate vaccines to prevent Mycobacterium tuberculosis (Mtb) infection and/or tuberculosis, and to increase the clinical pipeline of viable vaccine candidates.

Funding Opportunity RFA-AG-26-014 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) invites applications that propose interdisciplinary research that aims to develop complex mammalian 3-dimensional (3D)in vitromicrophysiological systems (MPS) to model aging and recapitulate aging processes/phenotypes observed in the whole organismin vivo. This NOFO is primarily focused on human cell-derived MPS (e.g., tissue chip, organ-on-chip, tissue organoids). However, systems developed using cells of nonhuman mammalian origin are acceptable for benchmarking, system validation, or when their relevance to understanding human aging biology is justified. Supported projects will be expected to advance the adoption of MPS in aging biology research and as new human-relevant tools for drug discovery. This NOFO uses the R21 activity code, which is intended for exploratory research at the early and conceptual stages of project development. Preliminary data are not required. An essential feature of responsive applications is the adoption of a multidisciplinary approach that includes expertise in aging biology and from disciplines such as stem cell biology, tissue and organ physiology, microfluidics, bioengineering, computational biology, pharmacology, and biostatistics.

Notice NOT-OD-25-150 from the NIH Guide for Grants and Contracts

Notice NOT-OD-25-148 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-AI-25-027 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to support the establishment of multidisciplinary Tuberculosis (TB) Research Units (TBRUs) that will operate as a collaborative network to improve understanding of Mycobacterium tuberculosis (Mtb)-host interactions through characterizing the roles of bacterial and host heterogeneity on infection outcomes and disease progression, and defining bacterial and host determinants relevant to Mtb establishment, dissemination, and disease stage.

Funding Opportunity RFA-AI-25-018 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to solicit applications from eligible organizations to participate in a cooperative research group, the Mucosal Immunology Studies Team (MIST), focusing on immune mechanisms and immune regulation at mucosal surfaces of the respiratory, gastrointestinal, and urogenital tracts. The main objective of this program is to break new ground in the understanding of basic mucosal immune mechanisms by introducing new ideas, approaches, and technologies that address difficult questions in mucosal immunology

Funding Opportunity PAR-25-441 from the NIH Guide for Grants and Contracts. The purpose of the Native American Research Centers for Health (NARCH) Planning Grants program is to support federally recognized American Indian/Alaska Native (AI/AN) Tribes, Tribal colleges and universities, Tribal health programs, or Tribal organizations (collectively, eligible AI/AN Tribal entities) to plan and conduct preparatory work for developing competitive NARCH applications.

Funding Opportunity PAR-25-322 from the NIH Guide for Grants and Contracts. The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Notice of Funding Opportunity (NOFO) must not include preliminary data. Applications must include a separate attachment describing the change in research direction.

Funding Opportunity PAR-25-323 from the NIH Guide for Grants and Contracts. The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Notice of Funding Opportunity Announcement (NOFO) must not include preliminary data. Applications must include a separate attachment describing the change in research direction. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. This Funding Opportunity is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies that are NOT conducted with specific applications toward processes or products in mind and which also do not meet the clinical trial definition should submit under the appropriate Clinical Trial Not Allowed NOFO .