Silk Microspheres and Methods for Surface Lubrication

Current lubricants used in arthritis treatment often degrade under inflammatory conditions. A clinically viable and effective formulation for the treatment of joint disorders such as osteoarthritis is needed. While phospholipids, alone, are ineffective in clinical use, silky microsphere partly comprised of phospholipids may be used to lower the friction coefficient, minimize surface wear, and avoid degradation, even under strenuous conditions. Silky microspheres can be used with biological and non-biological surfaces, such as between two surfaces of a machine or device.