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Leveraging Data at Scale to Understand Natural Product Impacts on Whole Person Health (R01 Clinical Trial Not Allowed)

3 weeks 2 days ago
Funding Opportunity RFA-AT-24-008 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) will support development, adaptation, and/or applications of computational tools to aggregate and analyze orthogonal chemical and/or biological data sets related to natural products with the aim of generating novel testable hypotheses regarding their biological activity and role in the context of whole person health research. Projects must leverage and merge multiple compatible or interoperable sources and/or types of data. Use of artificial intelligence and machine learning approaches is encouraged. This NOFO is part of the Consortium Advancing Research on Botanicals and Other Natural Products (CARBON) Program. Other components of this Program include the Botanical Dietary Supplements Translational Research Teams (RM1) and Limited Competition: Research Resource for Natural Product Nuclear Magnetic Resonance Data (R24).

Medical Scientist Training Program (MSTP) (T32)

3 weeks 3 days ago
Funding Opportunity PAR-24-128 from the NIH Guide for Grants and Contracts. The goal of the Medical Scientist Training Program (MSTP) is to develop a diverse pool of highly trained physician-scientist leaders available to meet the needs of the Nations biomedical research agenda. Specifically, this Notice of Funding Opportunity (NOFO) provides support to eligible domestic institutions to develop and implement effective, evidence-based approaches to integrated dual-degree training leading to the award of both professional medical doctorate degrees and research doctorate degrees (Ph.D. or equivalent). With the dual qualification of rigorous scientific research and clinical practice, graduates will be equipped with the skills to develop research programs that accelerate the translation of research advances to the understanding, detection, treatment and prevention of human disease, and to lead the advancement of biomedical research. Areas of particular importance to NIGMS are the iterative optimization of MSTP training efficacy and efficiency, fostering the persistence of MSTP alumni in research careers, and enhancing the diversity of the physician-scientist workforce. NIGMS expects that the proposed research training programs will incorporate didactic, research, mentoring and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the Nation.

Elucidating Mechanisms Associated with HIV Related Co-Morbidities in Populations Experiencing Health Disparities (R01 - Clinical Trials Not Allowed)

3 weeks 6 days ago
Funding Opportunity RFA-MD-24-005 from the NIH Guide for Grants and Contracts. The purpose of this initiative is to support research to determine the underlying mechanisms that contribute to health disparities in HIV and aging and how multiple comorbidities influence overall health outcomes and quality of life among people with HIV from populations that experience health disparities.

Impact of Comorbidities and Co-Infections on HIV Reservoirs (R01 Clinical Trial Not Allowed)

4 weeks ago
Funding Opportunity RFA-DK-25-013 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) seeks to foster new multi-disciplinary teams to address how HIV Comorbidities and co-infections within the missions of NIDDK and NIAID interact with viral reservoirs, potentially confounding cure strategies aimed at either sustained viral suppression or elimination from the body. These teams will mechanistically interrogate the impact of inflammation, metabolic perturbations, or other pathophysiological processes associated with these comorbidities or co-infections on reservoir dynamics, and/or the interplay of these conditions and co-infections on HIV reservoir biology in ways that are likely to interact with potential cure strategies.

Priority HIV/AIDS Research within the Mission of NIDDK (R01 Clinical Trial Optional)

4 weeks ago
Funding Opportunity PAS-24-163 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) seeks to stimulate HIV/AIDS research within the mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) that align with the HIV/AIDS research priorities outlined by the NIH Office of AIDS Research (OAR). These priorities were most recently described in NOT-OD-20-018 UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.