The Office of Research is pleased to announce two funding opportunities: 1.) A Request for Proposals (RFP) has been issued for a new Office of Research funded Centers of Excellence. A Letter of Intent (LOI) must be submitted no later than 11/1/24. Go HERE for the RFP and LOI details. 2.) Office of Research Bridge Fund Award applications will be accepted until 12/1/24. Go HERE for more information.

Mechanism for Time-Sensitive Substance Use Research (R21 Clinical Trial Optional)

1 month ago
Funding Opportunity PAR-24-298 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) will support pilot, feasibility or exploratory research in 5 priority areas in substance use epidemiology and health services, including: 1) responses to sudden and severe emerging drug issues (e.g. the ability to look into a large and sudden spike in opioid or synthetic cannabinoid use/overdoses in a particular community); 2) responses to emerging marijuana trends and topics related to the shifting policy landscape; 3) responses to unexpected and time-sensitive prescription drug abuse research opportunities (e.g., new state or local efforts); 4) responses to unexpected and time-sensitive medical system issues (e.g. opportunities to understand addiction services in the evolving health care system); and 5) responses to unexpected and time-sensitive criminal or juvenile justice opportunities (e.g. new system and/or structural level changes) that relate to drug abuse and access and provision of health care service. It should be clear that the knowledge gained from the proposed study is time-sensitive and that an expedited rapid review and funding are required in order for the scientific question to be answered (i.e. an imminent policy change will not allow for standard review and funding timeline).

HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)

1 month ago
Funding Opportunity RFA-NS-25-023 from the NIH Guide for Grants and Contracts. This funding opportunity is part of a suite of NOFOs within the NIH HEAL Initiative to support the development of safe, effective, and non-addictive therapeutics to treat pain. The goal is to encourage initial translational efforts that will support a drug discovery program and advance projects to the point where they meet the entry criteria for the Pain Therapeutics Development Program. The scope will therefore be focused on development of assays to support a distinct testing funnel, screening efforts to identify hits, and initial characterization of hits and potential therapeutic agents (including small molecules, biologics, and natural products).

U.S.-South Africa Program for Collaborative Biomedical Research Phase 3 (HIV/AIDS) (R01 Clinical Trial Optional)

1 month ago
Funding Opportunity RFA-AI-24-023 from the NIH Guide for Grants and Contracts. The purpose of this Notice of Funding Opportunity (NOFO) is to support research projects under Phase 3 of the U.S.-South Africa Program for Collaborative Biomedical Research. Research areas supported under this program include HIV/AIDS, HIV/AIDS co-morbidities and co-infections, HIV/AIDS-associated implementation science, and HIV/AIDS-associated data science. The hallmark of the U.S.-South Africa program is the development of collaborative partnerships between South African investigators and United States (U.S.) investigators. Through international collaboration, this research will advance scientific discoveries, promote sharing of technologies and approaches, and serve local public health needs and priorities in support of global HIV/AIDS research.

Imaging - Science Track Award for Research Transition (I/START) (R03 Clinical Trial Optional)

1 month ago
Funding Opportunity PAR-24-297 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity Announcement (NOFO) is designed to encourage and facilitate the entry of investigators to the area of brain imaging research. This NOFO will support both newly independent investigators and established investigators who are seeking to develop and adopt neuroimaging tools and methodologies in their research programs and conduct small "proof-of-concept" studies relevant to substance use disorders and addiction. This NOFO is intended to support Small Research Grant (R03) projects that can be carried out in a short period of time with limited resources.

Cellular Models of HIV Pathogenesis within NIDDK Mission Areas (R01 Clinical Trial Not Allowed)

1 month ago
Funding Opportunity RFA-DK-25-021 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites applications that are focused on developing, using, and/or improving cellular models that recapitulate critical aspects of normal human physiology, such as microphysiological systems, organoids, and other three-dimensional models, to explore the interaction of HIV with tissues and processes within NIDDK's mission areas. Projects are expected to investigate mechanisms of viral persistence, latency, reactivation, eradication, or pathological processes contributing to co-occurring conditions.

Research Centers in Minority Institutions (RCMI) (U54 - Clinical Trial Optional)

1 month 1 week ago
Funding Opportunity RFA-MD-24-012 from the NIH Guide for Grants and Contracts. The purpose of the Research Centers in Minority Institutions (RCMI) Program is to expand the national capacity for research in the health sciences by providing cooperative agreement support to institutions that offer doctorate degrees in the health professions or in a health-related science and have a documented historical mission and commitment to educating underrepresented students, and for institutions that provide clinical services to medically underserved communities.
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Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
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