Funding Opportunity PAR-24-098 from the NIH Guide for Grants and Contracts. (Reissue PAR-21-057) The purpose of this Program Announcement (PAR) is to enable analytical validation of strong candidate biomarkers for neurological diseases and conditions. Specifically, the goal of this PAR is to enable the rigorous validation of analytical methods for biomarker measurements, including evaluation of the detection method, its performance characteristics, and the optimal conditions that will generate reproducibility and accuracy consistent with FDA guidelines. This PAR assumes that 1) a candidate biomarker has already been identified, 2) detection method technology has already been developed, and 3) the research and/or clinical need and potential context of use has been identified.

Funding Opportunity RFA-OD-24-009 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO), issued by the Office of the Director (OD), National Institutes of Health (NIH), invites applications from entities/institutions in Institutional Development Award (IDeA)-eligible states to participate as the Data Coordinating and Operations Center (DCOC) in the Environmental influences on Child Health Outcomes IDeA States Pediatric Clinical Trials Network (ECHO ISPCTN). This RFA runs in parallel with companion RFA (Clinical Sites RFA-OD-***) that will solicit applications for ECHO ISPCTN Clinical Sites. The ECHO ISPCTN DCOC and Clinical Sites together will form the ECHO ISPCTN. The ECHO ISPCTN is the intervention component of the ECHO Program and supports its overall mission to enhance the health of children for generations to come. The DCOC award budget will fund approximately five multicenter pediatric clinical trials with each trial related to prevention or treatment of one or more of ECHOs five outcome areas of interest: pre-, peri-, and postnatal outcomes; upper and lower airways; obesity; neurodevelopment; and positive health. Overall, the five trials should address at least two of the five areas. The DCOC will support the ECHO ISPCTN Clinical Sites to Develop, conduct, and disseminate findings from multicenter clinical trials research, assuring the participation of children living in rural or underserved communities in IDeA states Build pediatric clinical trial research capacity in IDeA states funded by the ECHO ISPCTN Engage interested parties such as community members, nonprofit organizations, and professional societies to enhance ECHO ISPCTN clinical trial impact, transferability, rigor, and feasibility Through the rigorous use of appropriate scientific methodology and by recruiting and retaining the numbers of participants that justify multicenter trials, the ECHO ISPCTN aims to provide valid and generalizable answers to intervention research questions relevant to the health of children from rural

Funding Opportunity RFA-OD-24-008 from the NIH Guide for Grants and Contracts. This Notice of Funding opportunity (NOFO), issued by the Office of the Director (OD), National Institutes of Health (NIH), invites applications from entities/institutions in Institutional Development Award (IDeA)-eligible States to participate as Clinical Sites in the Environmental influences on Child Health Outcomes IDeA States Pediatric Clinical Trials Network (ECHO ISPCTN). This NOFO runs in parallel with companion NOFO (NOFO -OD-***) that will solicit applications for a Data Coordinating and Operations Center (DCOC) within the IDeA States. The ECHO ISPCTN Clinical Sites and DCOC together will form the ECHO ISPCTN. The ECHO ISPCTN is the intervention component of the ECHO program and supports its overall mission to enhance the health of children for generations to come. Each ISPCTN Clinical Site will support site readiness to participate in approximately five ECHO ISPCTN multicenter pediatric clinical trials related to prevention or treatment of one or more of ECHOs five outcome areas of interest: pre-, peri-, and postnatal outcomes; upper and lower airways; obesity; neurodevelopment; and positive health. Overall, the five trials should address at least two of the five areas. The Clinical Site will have responsibility to Develop, conduct, and disseminate findings from multicenter clinical trials research, assuring the participation of children living in rural or underserved communities in IDeA states Build pediatric clinical trial research capacity in IDeA states funded by the ECHO ISPCTN Engage interested parties such as community members, nonprofit organizations, and professional societies to enhance ECHO ISPCTN clinical trial impact, transferability, rigor, and feasibility Through the rigorous use of appropriate scientific methodology and by recruiting and retaining the numbers of participants that justify multicenter trials, the ECHO ISPCTN aims to provide valid and generalizable answers to intervention research questions relevant to the health

Notice NOT-NS-24-045 from the NIH Guide for Grants and Contracts

Notice NOT-RM-24-004 from the NIH Guide for Grants and Contracts

Notice NOT-NS-24-038 from the NIH Guide for Grants and Contracts

Notice NOT-NS-24-041 from the NIH Guide for Grants and Contracts

Notice NOT-ES-24-006 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-24-122 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) encourages applications for research in cancer control and population sciences. The overarching goal is to provide support to promote research efforts on novel scientific ideas that have the potential to substantially advance cancer research in statistical and analytic methods, epidemiology, cancer survivorship, cancer-related behaviors and behavioral interventions, healthcare delivery, and digital health and data science, and implementation science.

Notice NOT-DC-24-020 from the NIH Guide for Grants and Contracts

Funding Opportunity PAR-24-114 from the NIH Guide for Grants and Contracts. The purpose of the International Research Scientist Development Award (IRSDA) is to provide support and protected time (three to five years) to advanced postdoctoral U.S. research scientists and recently-appointed U.S. junior faculty (applicants must be at least two years beyond conferral of doctoral degree) for an intensive, mentored research career development experience in a low- or middle-income country (LMIC), as defined by the World Bank (http://data.worldbank.org/about/country-classifications/country-and-lending-groups, including "low-income," "lower-middle-income," and "upper-middle-income" countries) leading to an independently-funded research career focused on global health. This Funding Opportunity Announcement (FOA) invites applications from postdoctoral research scientists and junior faculty from any health-related discipline who propose career development activities and a research project that is relevant to the health priorities of the LMIC under the mentorship of LMIC and U.S. mentors.

Notice NOT-MD-24-005 from the NIH Guide for Grants and Contracts

Notice NOT-AT-24-030 from the NIH Guide for Grants and Contracts

Notice NOT-OD-24-044 from the NIH Guide for Grants and Contracts

Funding Opportunity RFA-DA-25-060 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

Notice NOT-NS-24-048 from the NIH Guide for Grants and Contracts

Notice NOT-NS-24-040 from the NIH Guide for Grants and Contracts

Notice NOT-MH-24-155 from the NIH Guide for Grants and Contracts

Notice NOT-GM-24-018 from the NIH Guide for Grants and Contracts

Notice NOT-DC-24-018 from the NIH Guide for Grants and Contracts