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Weekly Funding Opportunities and Policy Notices from the National Institutes of Health.
Updated: 19 hours 11 min ago

National Cancer Institute Program Project Applications for the Years 2023, 2024, and 2025 (P01 Clinical Trial Optional)

Wed, 12/14/2022 - 08:05
Funding Opportunity PAR-23-059 from the NIH Guide for Grants and Contracts. Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites applications for investigator-initiated Program Project (P01) applications. The proposed Program may address any of the broad areas of cancer research, including (but not limited to) cancer biology, cancer prevention, cancer diagnosis, cancer treatment, and cancer control. Basic, translational, clinical, and/or population-based studies in all of these research areas are appropriate. Each application submitted in response to this FOA must consist of at least three research projects and an Administrative Core. The projects must share a common central theme, focus, and/or overall objective.

Notice of Special Interest (NOSI): Optimization of Data Storage and Utilization for the Sequence Read Archive (SRA)

Wed, 12/14/2022 - 07:55
Notice NOT-GM-23-015 from the NIH Guide for Grants and Contracts

Co-infection and Cancer (R21 Clinical Trial Not Allowed)

Wed, 12/14/2022 - 04:38
Funding Opportunity PAR-23-056 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to enhance mechanistic and epidemiologic investigations addressing the roles of co-infection and cancer to shed light on presently unestablished pathways in carcinogenesis that may inform prevention and treatment strategies for infection-related cancers. Co-infection is defined as the occurrence of infections by two or more infectious (pathogenic or non-pathogenic) agents either concurrently or sequentially and includes both acute and chronic infections by viruses, bacteria, parasites, and/or other microorganisms. Preference will be given to investigations of co-infections with known oncogenic agents (excluding human immunodeficiency virus [HIV]) and of co-infections that engender novel opportunities for prevention and treatment.

Co-infection and Cancer (R01 Clinical Trial Not Allowed)

Wed, 12/14/2022 - 04:31
Funding Opportunity PAR-23-055 from the NIH Guide for Grants and Contracts. This initiative seeks to enhance our mechanistic and epidemiologic understanding of infection-related cancers, with a focus on the etiologic roles of co-infection in cancer. Preference will be given to co-infections (excluding co-infection with human immunodeficiency virus [HIV]) that engendered novel opportunities for prevention and treatment and focus on understudied populations. Coinfection is defined as the occurrence of infections by two or more infectious (pathogenic or nonpathogenic) agents either concurrently or sequentially and includes both acute and chronic infections by viruses, bacteria, parasites, and/or other microorganisms.

Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Independent Clinical Trial Not Allowed)

Tue, 12/13/2022 - 10:37
Funding Opportunity RFA-OD-23-003 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this OBSSR R25 program is to support educational activities that complement and/or enhance the training of a diverse workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Courses for Skills Development

Clinical Studies of Mental Illness (Collaborative R01) (Clinical Trial Optional)

Tue, 12/13/2022 - 10:31
Funding Opportunity PAR-23-050 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) seeks to support collaborative clinical studies, not involving treatment development, efficacy, or effectiveness trials. Primary areas of focus include mental health genetics, biomarker studies, and studies of mental illnesses (e.g., psychopathology, neurodevelopmental trajectories of psychopathology) also when associated with HIV/AIDS. Applicants should apply to this FOA when two or more sites are needed to complete the study. Accordingly, the collaborating studies share a specific protocol across the sites and are organized as such in order to increase sample size, accelerate recruitment, or increase sample diversity and representation. In studies with a large number of sites, it is expected that one site will be submitted as a coordinating R01 for data management and/or other centralized administration.

Research on Community Level Interventions for Firearm and Related Violence, Injury and Mortality Prevention (CLIF-VP) (UG3/UH3 Clinical Trial Required)

Tue, 12/13/2022 - 02:14
Funding Opportunity PAR-23-066 from the NIH Guide for Grants and Contracts. Violence affects people of all ages and its impact is far-reaching. It is a leading cause of death and nonfatal injuries in the United States and constitutes a major public health crisis, especially among young people, and in particular among racial/ethnic minority, sexual and gender minority (SGM) and disability populations. NIH is committed to supporting research that identifies innovative prevention approaches to reduce firearm and related violence, injury and mortality. Within the legislative mandates and limitations of NIH funding (NOT-OD-21-058, NOT-OD-21-056), this initiative will support a network of research projects to develop and test interventions at the community or community organization level that aim to prevent firearm and related violence, injury and mortality

Notice of Future Research Opportunity Announcement for the All of Us Center for Linkage and Acquisition of Data

Mon, 12/12/2022 - 08:25
Notice NOT-PM-23-002 from the NIH Guide for Grants and Contracts

Rapid Translation of Epidemiological Findings into Interventions to Prevent Substance Use and Addiction (R61/R33 Clinical Trial Optional)

Mon, 12/12/2022 - 04:14
Funding Opportunity RFA-DA-24-010 from the NIH Guide for Grants and Contracts. The goal of this initiative is to address the structural incentives that limit translation from epidemiology into prevention science using a two-pronged approach. The phased R61/R33 mechanism will support innovative epidemiologic research using either primary data collection or analysis of existing data related to substance use and addiction in the R61 phase to provide the foundation for a targeted prevention intervention in the R33 phase. The R33 phase would apply the findings from the R61 phase to either a) adapt or target an existing intervention to increase effect size or reach a new population or b) develop a novel intervention to address a new prevention target. Applicants would be required to use an MPI/MPD structure so that there is a PI with relevant expertise to lead the different components of the project. The supplement mechanism will capitalize on bidirectional translational science wherein existing epidemiological projects can submit proposals to test prevention hypotheses as well as prevention interventions can submit proposals for additional epidemiological inquiry to help contextualize their findings.

Interorgan Communication in Aging (U01 Clinical Trial Not Allowed)

Mon, 12/12/2022 - 04:10
Funding Opportunity RFA-AG-24-005 from the NIH Guide for Grants and Contracts. The goal of this RFA is to foster research that examines the molecular mechanisms and consequences of age-related alterations in interorgan communication, thereby modulating the age-related decline in homeostasis thus contributing to the heterogeneity of aging.

Notice of Intent to Publish a Funding Opportunity Announcement for Reporting Back Environmental Health and Non-Genomic Research Results

Fri, 12/09/2022 - 11:00
Notice NOT-ES-23-003 from the NIH Guide for Grants and Contracts

Notice of Pre-Application Webinar for NHLBI SBIR Phase IIB Small Market Awards and Bridge Awards (RFA-HL-23-008 and RFA-HL-23-009)

Thu, 12/08/2022 - 11:00
Notice NOT-HL-22-062 from the NIH Guide for Grants and Contracts

Development of Animal Models and Related Biological Materials for Down Syndrome Research (R21 Clinical Trials Not Allowed)

Thu, 12/08/2022 - 01:59
Funding Opportunity PAR-23-067 from the NIH Guide for Grants and Contracts. The INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project encourages exploratory and innovative research to develop, characterize, or improve animal models and related biological materials for Down syndrome (DS) related research and to improve access to information about or from the use of animal models for DS research. The animal models and related biological materials developed must have utility in targeted or basic science studies in areas highly relevant to DS. With this funding opportunity announcement, the INCLUDE Project encourages, but is not limited to, projects focusing on development of various animal models, genetic resources, atlases at a single cell or subcellular level, advanced informatics technologies including artificial intelligence (AI) or machine learning (ML), and integration of multiple animal models and technology platforms for enhancing rigor and reproducibility of preclinical DS research.

Research Networks to Promote Multidisciplinary Mechanistic Studies on Music-Based Interventions for Pain or Alzheimers Disease and Alzheimers Disease Related Dementias (AD/ADRD) (U24 Clinical Trial Optional)

Thu, 12/08/2022 - 01:28
Funding Opportunity RFA-AT-23-008 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to support a collection of research networks that promote multidisciplinary mechanistic studies of music-based interventions (MBIs) for pain or Alzheimers disease and Alzheimers disease related dementias (AD/ADRD). These networks are expected to develop compelling research frameworks that will guide future clinical research on MBIs in these health conditions effectively, adopt consistent terminology and taxonomy, support interdisciplinary collaborations, initiate pilot projects testing novel mechanistic hypotheses, and identify strong mechanistic measures, outcomes, biomarkers, as well as relevant novel technologies and methodologies. To accomplish these objectives, applicants can propose activities such as meetings, workshops, conferences, research collaborations, exchange of ideas through visiting scientist arrangements and training opportunities. The research networks would also provide opportunities for development of pilot projects addressing research gaps identified through network meetings and collaborative discussions, providing the necessary preliminary data needed for music and health investigators to compete for more substantial NIH grants. In addition, the networks should also engage in dissemination activities that promote and sustain their scientific impact through publications of research frameworks, common terminologies, reviews, and best practices as well as other outreach and communication strategies.