Method to identify high proliferation potential and senescence in MSCs

Background

Tulane University is actively seeking commercial entities to further develop and commercialize a method relating to the identification and isolation of mesenchymal stem cells (MSCs) with a desired differentiation potential and/or senescence using immunophenotyping.

Applications

Immediate use of selected cells for patients. Selection and culture of MSCs capable of high proliferation. Selection and culture of MSCs that are not senescent. Identification, isolation and further culture of MSCs to produce an enriched population of cells. Specific amplification of stem cell populations with a desired differentiation potential. Quantification of the heterogeneity and differentiation potential of a stem cell culture. Minimal damage to cells. Selective for multipotent MSCs that are capable of high proliferation and/or not senescent. Identification of cell surface markers of early MSC aging. May be used for all mammals, including veterinary therapeutics and research. Applicable for autologous and allogenic therapies